BOTANICAL COMPLEX B19

COMPLEX B19 contains the plants, with their scientific names: Urtica urens, Hedera helix, Rosmarinus officinalis and Equisetum arvense; in daily life known as Nettle, Ivy, Rosemary and Horsetail.

Biota has developed an effective, patented herbal extract against hair loss.

(Patent Application Number: 2019/08987, Application Date: 18-06-2019).

This herbal cosmetic blend not only delivers antioxidant benefits but also stimulates the growth of dermal keratinocytes and fibroblasts. As a result, it serves as a potent active ingredient in hair loss prevention products.

In BIOBLAS shampoo and serum, Complex B19 is the key active ingredient and has been dermatologically tested to ensure both its safety and effectiveness.

Complex B19

CELL CULTURE STUDIES

The human keratinocyte cell line (HaCaT) and

the human fibroblast cell line (HFC 1184, Sigma Aldrich) were used.

STUDY STEPS:

XXT Cell Proliferation

RNA Isolation

Reverse Transcription

Real-time PCR (Quantitative Polymerase Chain Reaction)

In Vitro Studies

Based on the in vitro gene expression results from the tested plants, Complex B19 decreased the level of cellular factors that lead to hair loss and increased the level of factors that support hair growth. These positive results observed in the cell culture study are the result of the patented herbal extract used in the formulation of BIOBLAS shampoo and serum.